Paige and Microsoft Research released PRISM2, a 4.4-billion-parameter model that reads digitised microscope slides of tissue and answers questions about them in text, including drafting report-style descriptions. It is published on Hugging Face under a licence limited to non-commercial academic research, with access granted only to registered institutional users. Clinical or diagnostic use is explicitly prohibited, and the model needs pre-computed tile embeddings from Paige's Virchow2 rather than raw slide images.
What changed
Paige's earlier pathology models produced slide embeddings without built-in text dialogue.
What it unlocks
Generating draft pathology descriptions and yes/no answers from whole-slide image embeddings in a research setting.
- 4.4B parameters total
- 2.3M whole slide images in training
- 14M question-answer pairs
What you need to act on it
- Hugging Face account with institutional email and approved access request
- CUDA-capable GPU
- pre-extracted Virchow2 tile embeddings
- non-commercial academic research use only
Sources