Noesion Radarnoesion.ai
Release2026-08-04

Paige, working with Microsoft Research, released PRISM2, a 4.4-billion-parameter multimodal foundation model for slide-level analysis of H&E-stained histopathology images, on Hugging Face under a CC-BY-NC-ND 4.0 license restricted to non-commercial academic research. The model pairs a 0.6B-parameter Perceiver whole-slide-image encoder with a Phi-3-mini-128k-instruct decoder (3.8B) and consumes pre-extracted Virchow2 tile embeddings at 20x magnification and 224x224 tiles rather than raw slides. Supported modes include base (2560-dim) and diagnostic (3072-dim) slide embeddings, yes/no question scoring, report generation, and open-ended or multiple-choice question answering. Pretraining used an internal set of 2.3 million whole slide images from 685,507 specimens (200,692 patients) and 14 million question-answer pairs derived from Memorial Sloan Kettering Cancer Center clinical reports.

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